Windows Defender Error 0x80073afc is usually caused by a corrupted file or folder in the Windows Defender program. This can happen if the program is not properly installed, or if a virus or other malicious software has corrupted the program.
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1. Try restarting your computer and then opening Windows Defender
- Restart your computer.
 - After your computer restarts, open the task manager by pressing CTRL+ALT+DEL.
 - In the task manager, click on the process with the error message.
 - On the properties of the process, click on the end task button.
 - In the end task window, select the restart button.
 - After your computer restarts, open Windows Defender.
 
2. Check for updates to Windows Defender
- Open the Control Panel by clicking on Start, Control Panel and then clicking on Windows Defender.
 - On the Windows Defender window, click on the Update tab.
 - On the Update tab, select Check for updates and then click on the Check for updates button.
 - If available, Windows Defender will start to search for updates and then will display a list of available updates.
 - Click on the update that you want to install and then click on the Install button.
 - After the update has been installed, Windows Defender will restart.
 
3. Try running a full scan with Windows Defender
- Open the Start menu and click on the Windows Defender icon.
 - Click on the "Scan Now" button.
 - If the "Scan Now" button is not available, you can access it by clicking on the "Scan" tab on the main window.
 - Click on the "Advanced" button.
 - Under "Scan Type," select "Full Scan."
 - Click on the "Start Scan" button.
 - If the "Start Scan" button is not available, you can access it by clicking on the "Advanced" button and then on the "Start Scan" button.
 - Windows Defender will start scanning your computer for viruses and other malware.
 - When the scan is complete, Windows Defender will display a progress bar and will give you the option to save the scan results.
 - Click on the "Save" button.
 - Windows Defender will save the scan results to a file on your computer.
 
If the answers above didn't work then you should also try:
- Temporarily disable any other security software you have running on your computer and then try opening Windows Defender again.
 - Uninstall any other security software you have running on your computer.
 - Perform a clean boot of your computer and then try opening Windows Defender again.
 - Reinstall Windows Defender.
 
